Innocell™ / Personalized cellular immunotherapy

A broader view
of cancer.

Every tumor carries a different set of antigens. Innocell starts with the patient’s own tumor cells to preserve that breadth.

Discover the science
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A tumor’s own signature.

A patient’s tumor cells carry many different antigens. Those surface signals are the starting point for Innocell.

Patient-derived tumor cell · Surface antigens in gold

Conceptual cutaway of a tumor cell showing its internal structure and surface antigens.

Drag to explore the cell. Choose a stage to follow the process.

Conceptual cellular illustration

Conceptual illustration · Not to scale. Innocell is investigational.

In clinical development

Phase 1 study at City of Hope

Innocell for recurrent
epithelial ovarian cancer

Explore the study

The tumor supplies the targets.

Solid tumors are heterogeneous: their cells can carry different antigens. Innocell keeps the patient’s broad tumor-antigen repertoire, rather than selecting a small set of targets.

The patient’s tumor cellsA broad repertoire of tumor antigens
Conceptual illustration · Not to scale

Personalized at the source

The patient’s tumor supplies the antigens. The approach preserves their breadth through the inactivation process.

Prepared without cell expansion

One tissue preparation can yield multiple doses. A turnaround of less than seven days is anticipated at commercial scale.

How Innocell works Conceptual process diagram: Collect then Inactivate then Administer then Target. Collect The patient's tumor cells Inactivate Riboflavin + UV light Administer Innocell + CpG1018 Target Intended immune response

Innocell is investigational. Safety and immunogenicity are being evaluated in a Phase 1 study. The illustration explains the proposed mechanism; it does not depict clinical results.

Research and publications

Clinical development

Starting with recurrent ovarian cancer.

Lead program

Innocell, recurrent epithelial ovarian cancer

Phase 1, City of Hope

An FDA-cleared study evaluating safety and immunogenicity. ClinicalTrials.gov NCT06366490.

View clinical study

Innocell with bevacizumab, ovarian cancer

Phase 1b planned

A planned combination cohort in the ovarian cancer program.

Lung, colorectal, breast, melanoma

Preclinical development

Potential expansion into additional solid tumors.

Canine cancer

Published case study

Early translational work reported by Goodrich et al., J. Immunol. Res. (2020).

US patent 12,280,039 covers Innocell compositions. Innocell is an investigational therapy and is not approved for commercial use.

Talk to us.

Connect with our team.

admin@photonpharma.net

PhotonPharma, Inc., Research Innovation Center, 3185 Rampart Road, Fort Collins, CO 80523.

Research Innovation Center at Colorado State University

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